Genomic Heterogeneity of the Naga and Kuki Tribal Populations of Manipur, Northeast India

Manipur, one of the northeastern states India, lies on ancient silk route and serves as a meeting point between Southeast Asia South Asia. The origin migration histories Naga Kuki tribal populations are not clearly understood. Moreover, Kukis have been traced to two different ancestries, which has created confusion among people. present study examined genomic affinities differentiation Northeast India. Twenty autosomal markers (8 Alu insertion-deletions, 12 restriction-fragment-length polymorphisms) were analyzed. Findings show genetic differences with respect allele distribution pattern, was substantiated by (GST = 5.2%) molecular variance (AMOVA), where highest percentage among-group variances observed groups (7.09%). However, similarities patterns in most loci seen their respective (Rongmei Inpui, Thadou Vaiphei). Rongmei Inpui (Naga group) belong Naga-Bodo linguistic group, Vaiphei (Kuki Northern Kuki-Chin suggesting that may be independent affinities. Despite differential affinities, both Manipur more proximity Asian Indian than other global taken for comparison.